MZB1 Antibody

1. expression was positively correlated with a high accumulation of CD8(+) tumor-infiltrating lymphocytes in pancreatic ductal adenocarcinoma after neoadjuvant chemoradiotherapy PMID: 29180208
2. Low MZB1 expression was an independent prognostic factor for recurrence after curative gastrectomy and was associated significantly with increased hematogenous recurrence. MZB1 acts as a suppressor of GC. Low MZB1 expression in the primary GC tissue is predictive of recurrence after curative resection. PMID: 27459504
3. High expression of MZB1 predicts adverse prognosis in chronic lymphocytic leukemia, follicular lymphoma and diffuse large B-cell lymphoma and is associated with a unique gene expression signature. PMID: 23189934
4. miR-185 regulates T cell development through its targeting of several mRNAs including Mzb1. PMID: 24014023
5. results suggested that MGC29506 has the potential of functioning as a novel suppressor gene in gastric cancer PMID: 23434460
6. methylation-mediated silencing of MZB1 expression leads to loss of its tumor-suppressive activity, which may be a factor in hepatocarcinogenesis PMID: 22573353
7. Data show that proapoptotic caspase adapter protein PACAP is a potential serum marker of non-small cell lung cancer. PMID: 22613335
8. MGC29506 gene, frequently down-regulated in intestinal-type gastric cancer, was found to encode secreted-type protein with six conserved cysteine residues [MGC29506] PMID: 12792799

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HGNC: 30125

OMIM: 609447

KEGG: hsa:51237

STRING: 9606.ENSP00000303920

UniGene: Hs.409563