N Antibody

Datasheet

Code	CSB-PA318492LA01JAM
Size	US$166
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Image	Western Blot Positive WB detected in Recombinant protein All lanes: N antibody at 3µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution predicted band size: 64 kDa observed band size: 64 kDa
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Target Background

Product Details

Full Product Name

Rabbit anti-Junin mammarenavirus N Polyclonal antibody

Uniprot No.

P14239

Target Names

Alternative Names

N antibody; Nucleoprotein antibody; EC 3.1.13.- antibody; Nucleocapsid protein antibody; Protein N antibody

Raised in

Rabbit

Species Reactivity

Junin mammarenavirus

Immunogen

Recombinant Junin mammarenavirus Nucleoprotein protein (1-564AA)

Immunogen Species

Junin mammarenavirus

Conjugate

Non-conjugated

The N Antibody (Product code: CSB-PA318492LA01JAM) is Non-conjugated. For N Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA318492LB01JAM	N Antibody, HRP conjugated	ELISA
FITC	CSB-PA318492LC01JAM	N Antibody, FITC conjugated
Biotin	CSB-PA318492LD01JAM	N Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.

Subcellular Location

Virion. Host cytoplasm.

Protein Families

Arenaviridae nucleocapsid protein family

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