NAAA Antibody, FITC conjugated

1. Variants a1 and a2 encoded the same full-length NAAA protein. PMID: 27693242
2. The results suggest that N-acylethanolamine acid amidase and protein tyrosine kinase 7 may be used as potential tissue biomarkers to avoid overtreatment of non-aggressive prostate cancer PMID: 24741114
3. MALDI-TOF MS analysis of the human NAAA zymogen (47.7 kDa) treated with peptide-N-glycosidase F (PNGase F) identified 4 glycosylation sites, and acid cleavage of the zymogen into alpha- and beta-subunits (14.6 and 33.3 kDa) activated the enzyme. PMID: 22040171
4. The level and activity of acid ceramidase in Alzheimer disease (AD) brain may play a role in controlling neuronal apoptosis and may mediate signalling pathways involved in the molecular mechanism of AD. PMID: 15610181
5. Asn-37, Asn-107, Asn-309, and Asn-333 are actual N-glycosylation sites. The glycosylation appeared to play an important role in stabilizing the enzyme protein. PMID: 17980170
6. we describe the overexpression and processing of recombinant human acid ceramidase in insect cells, its purification and characterization PMID: 18020949
7. These results showed that both N-acylethanolamine-hydrolysing acid amidase and fatty acid amide hydrolase are functionally active in human prostate cancer cells. PMID: 18806270

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HGNC: 736

OMIM: 607469

KEGG: hsa:27163

STRING: 9606.ENSP00000286733

UniGene: Hs.437365