NAAA Antibody, HRP conjugated

Datasheet

Code	CSB-PA22919B0Rb
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) NAAA Polyclonal antibody

Uniprot No.

Q02083

Target Names

NAAA

Alternative Names

Acid ceramidase like protein antibody; Acid ceramidase-like protein antibody; ASAH like protein antibody; ASAH-like protein antibody; N acylethanolamine acid amidase antibody; N acylethanolamine hydrolyzing acid amidase antibody; N acylsphingosine amidohydrolase (acid ceramidase) like antibody; N acylsphingosine amidohydrolase like antibody; N acylsphingosine amidohydrolase like protein antibody; N-acylethanolamine-hydrolyzing acid amidase subunit beta antibody; N-acylsphingosine amidohydrolase-like antibody; Naaa antibody; NAAA_HUMAN antibody; PLT antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human N-acylethanolamine-hydrolyzing acid amidase protein (29-199AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N-palmitoylethanolamine > N-myristoylethanolamine > N-lauroylethanolamine = N-stearoylethanolamine > N-arachidonoylethanolamine > N-oleoylethanolamine. Also exhibits weak hydrolytic activity against the ceramides N-lauroylsphingosine and N-palmitoylsphingosine.

Gene References into Functions

Variants a1 and a2 encoded the same full-length NAAA protein. PMID: 27693242
The results suggest that N-acylethanolamine acid amidase and protein tyrosine kinase 7 may be used as potential tissue biomarkers to avoid overtreatment of non-aggressive prostate cancer PMID: 24741114
MALDI-TOF MS analysis of the human NAAA zymogen (47.7 kDa) treated with peptide-N-glycosidase F (PNGase F) identified 4 glycosylation sites, and acid cleavage of the zymogen into alpha- and beta-subunits (14.6 and 33.3 kDa) activated the enzyme. PMID: 22040171
The level and activity of acid ceramidase in Alzheimer disease (AD) brain may play a role in controlling neuronal apoptosis and may mediate signalling pathways involved in the molecular mechanism of AD. PMID: 15610181
Asn-37, Asn-107, Asn-309, and Asn-333 are actual N-glycosylation sites. The glycosylation appeared to play an important role in stabilizing the enzyme protein. PMID: 17980170
we describe the overexpression and processing of recombinant human acid ceramidase in insect cells, its purification and characterization PMID: 18020949
These results showed that both N-acylethanolamine-hydrolysing acid amidase and fatty acid amide hydrolase are functionally active in human prostate cancer cells. PMID: 18806270

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Subcellular Location

Lysosome. Membrane; Peripheral membrane protein.

Protein Families

Acid ceramidase family

Tissue Specificity

Expressed in numerous tissues, with highest levels in liver and kidney, followed by pancreas.

Database Links

HGNC: 736

OMIM: 607469

KEGG: hsa:27163

STRING: 9606.ENSP00000286733

UniGene: Hs.437365

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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