NABP1 Antibody

Datasheet

Code	CSB-PA016249GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q96AH0

Target Names

NABP1

Alternative Names

FLJ13624 antibody; FLJ22833 antibody; hSSB2 antibody; MGC111163 antibody; Nabp1 antibody; Nucleic acid-binding protein 1 antibody; OBFC2A antibody; Oligonucleotide/oligosaccharide binding fold containing 2A antibody; Oligonucleotide/oligosaccharide binding fold containing protein 2A antibody; Oligonucleotide/oligosaccharide-binding fold-containing protein 2A antibody; Sensor of single strand DNA complex subunit B2 antibody; Sensor of single-strand DNA complex subunit B2 antibody; Sensor of ssDNA subunit B2 antibody; Single stranded DNA binding protein 2 antibody; Single-stranded DNA-binding protein 2 antibody; SOSB2_HUMAN antibody; SOSS B2 antibody; SOSS complex subunit B2 antibody; SOSS-B2 antibody; SSB2 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human OBFC2A

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.

Gene References into Functions

SNPs rs11903757, with closest proximity to NABP1 and SDPR, and rs966423 in DIRC3, were associated with survival in laryngeal squamous cell carcinoma patients. PMID: 27793000
hSSB1 and hSSB2 form two separate complexes with similar structures, and both complexes participate in DNA damage response. PMID: 19605351

Subcellular Location

Nucleus. Note=Localizes to nuclear foci following DNA damage.

Protein Families

SOSS-B family, SOSS-B2 subfamily

Database Links

HGNC: 26232

OMIM: 612103

KEGG: hsa:64859

STRING: 9606.ENSP00000403683

UniGene: Hs.591610

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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