NAGK Antibody

Code CSB-PA883457HA01HU
Size US$166
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Image
  • Western blot
    All lanes: N-acetyl-D-glucosamine kinase antibody at 2μg/ml
    Lane 1: HepG2 whole cell lysate
    Lane 2: 293T whole cell lysate
    Lane 3: Hela whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 38, 43 kDa
    Observed band size: 38 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NAGK Polyclonal antibody
Uniprot No.
Target Names
NAGK
Alternative Names
EC 2.7.1.59 antibody; GlcNAc kinase antibody; GNK antibody; HSA242910 antibody; N acetylglucosamine kinase antibody; N-acetyl-D-glucosamine kinase antibody; N-acetylglucosamine kinase antibody; nagK antibody; NAGK_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human N-acetyl-D-glucosamine kinase protein (2-344AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The NAGK Antibody (Product code: CSB-PA883457HA01HU) is Non-conjugated. For NAGK Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA883457HB01HU NAGK Antibody, HRP conjugated ELISA
FITC CSB-PA883457HC01HU NAGK Antibody, FITC conjugated
Biotin CSB-PA883457HD01HU NAGK Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity.
Gene References into Functions
  1. Data shows associations between NAGK, speckle, paraspeckle and general transcription factor suggesting its regulatory roles in gene expression. PMID: 25921606
  2. Participants with homozygous mutations in the N-acetylmannosamine kinase (GNK) domain have an earlier disease onset than heterozygous participants with mutations in the uridine diphosphate-N-acetylglucosamine 2-epimerase (GNE) and GNK domains. PMID: 22507750
  3. The cell-free system was validated for MNK activity, and it revealed that mutations in one enzymatic domain (in MNK, A631V, M712T) affected not only that domain's enzyme activity, but also the activity of the other domain. PMID: 15987957
  4. Phosphorylation of Tyr205 may modulate GlcNAc kinase activity and/or specificity. PMID: 17010375
Protein Families
Eukaryotic-type N-acetylglucosamine kinase family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 17174

OMIM: 606828

KEGG: hsa:55577

STRING: 9606.ENSP00000389087

UniGene: Hs.7036

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