NAPA Antibody, FITC conjugated

Code CSB-PA015447LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NAPA Polyclonal antibody
Uniprot No.
Target Names
NAPA
Alternative Names
Alpha soluble NSF attachment protein antibody; Alpha-soluble NSF attachment protein antibody; N ethylmaleimide sensitive factor attachment protein alpha antibody; N-ethylmaleimide-sensitive factor attachment protein alpha antibody; napA antibody; NSF attachment protein alpha antibody; SNAA_HUMAN antibody; SNAP alpha antibody; SNAP-alpha antibody; SNAPA antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Alpha-soluble NSF attachment protein (1-295AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane.
Gene References into Functions
  1. alphaSNAP is mainly expressed in the neuron brain tissue of patients with temporal lobe epilepsy. Its blood levels were significantly lower in these patients. alphaSNAP levels may increase epilepsy susceptibility. PMID: 26156199
  2. data implicates beta1 integrin, FAK, and paxillin in mediating the observed pro-adhesive effects of alphaSNAP. These results reveal novel roles for alphaSNAP in regulating ECM adhesion and motility of epithelial cells. PMID: 24311785
  3. Study revealed a novel role for alphaSNAP as a negative regulator of autophagy that acts by enhancing mTOR signaling and regulating the integrity of the Golgi complex. PMID: 23187805
  4. novel roles for alphaSNAP in promoting the formation of epithelial adherens junctions and tight junctions by controlling golgi-dependent expression and trafficking of junctional proteins. PMID: 22485163
  5. The most N-terminal part of BKV agnoprotein is involved in the interaction with alpha-SNAP PMID: 21931730
  6. a novel role for alphaSNAP in promoting epithelial cell survival by unique mechanisms involving regulation of Bcl-2 expression and Golgi biogenesis PMID: 22194596
  7. alpha-SNAP plays a key role in the acrosome reaction. PMID: 15542541
  8. G alpha12 interaction with alphaSNAP induces VE-cadherin localization at endothelial junctions and regulates barrier function PMID: 15980433

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Subcellular Location
Cell membrane; Peripheral membrane protein.
Protein Families
SNAP family
Database Links

HGNC: 7641

OMIM: 603215

KEGG: hsa:8775

STRING: 9606.ENSP00000263354

UniGene: Hs.126938

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