NAPA Recombinant Monoclonal Antibody

Datasheet

Code	CSB-RA441466A0HU
Size	US$210
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Image	IHC image of CSB-RA441466A0HU diluted at 1:100 and staining in paraffin-embedded human colorectal cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

P54920

Target Names

NAPA

Alternative Names

Alpha soluble NSF attachment protein antibody; Alpha-soluble NSF attachment protein antibody; N ethylmaleimide sensitive factor attachment protein alpha antibody; N-ethylmaleimide-sensitive factor attachment protein alpha antibody; napA antibody; NSF attachment protein alpha antibody; SNAA_HUMAN antibody; SNAP alpha antibody; SNAP-alpha antibody; SNAPA antibody

Species Reactivity

Human

Immunogen

A synthesized peptide from human NAPA protein

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Monoclonal

Isotype

Rabbit IgG

Clone No.

7F4

Purification Method

Affinity-chromatography

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane.

Gene References into Functions

alphaSNAP is mainly expressed in the neuron brain tissue of patients with temporal lobe epilepsy. Its blood levels were significantly lower in these patients. alphaSNAP levels may increase epilepsy susceptibility. PMID: 26156199
data implicates beta1 integrin, FAK, and paxillin in mediating the observed pro-adhesive effects of alphaSNAP. These results reveal novel roles for alphaSNAP in regulating ECM adhesion and motility of epithelial cells. PMID: 24311785
Study revealed a novel role for alphaSNAP as a negative regulator of autophagy that acts by enhancing mTOR signaling and regulating the integrity of the Golgi complex. PMID: 23187805
novel roles for alphaSNAP in promoting the formation of epithelial adherens junctions and tight junctions by controlling golgi-dependent expression and trafficking of junctional proteins. PMID: 22485163
The most N-terminal part of BKV agnoprotein is involved in the interaction with alpha-SNAP PMID: 21931730
a novel role for alphaSNAP in promoting epithelial cell survival by unique mechanisms involving regulation of Bcl-2 expression and Golgi biogenesis PMID: 22194596
alpha-SNAP plays a key role in the acrosome reaction. PMID: 15542541
G alpha12 interaction with alphaSNAP induces VE-cadherin localization at endothelial junctions and regulates barrier function PMID: 15980433

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Subcellular Location

Cell membrane; Peripheral membrane protein.

Protein Families

SNAP family

Database Links

HGNC: 7641

OMIM: 603215

KEGG: hsa:8775

STRING: 9606.ENSP00000263354

UniGene: Hs.126938

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

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Related pathways

Synaptic vesicle cycle

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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