CIAO3 Antibody

Datasheet

Code	CSB-PA863991LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: A549 whole cell lysate All lanes: CIAO3 antibody at 2.7µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 54, 27, 43 kDa Observed band size: 54, 27 kDa Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA863991LA01HU at dilution of 1:100 Immunofluorescent analysis of U251 cells using CSB-PA863991LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CIAO3 Polyclonal antibody

Uniprot No.

Q9H6Q4

Target Names

CIAO3

Alternative Names

CIAO3 antibody; NARFL antibody; PRNCytosolic iron-sulfur assembly component 3 antibody; Cytosolic Fe-S cluster assembly factor NARFL antibody; Iron-only hydrogenase-like protein 1 antibody; IOP1 antibody; Nuclear prelamin A recognition factor-like protein antibody; Protein related to Narf antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Cytosolic iron-sulfur assembly component 3 protein (2-265AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CIAO3 Antibody (Product code: CSB-PA863991LA01HU) is Non-conjugated. For CIAO3 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA863991LB01HU	CIAO3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA863991LC01HU	CIAO3 Antibody, FITC conjugated
Biotin	CSB-PA863991LD01HU	CIAO3 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.

Gene References into Functions

we concluded that the Ser161Ile mutant induced NARFL deficiency and eventually diffuse PAVMs probably through VEGF pathway. In a word, we detected a functional mutation in NARFL, which might be the pathogenic gene in this pedigree. PMID: 27835862
IOP1 is involved in mammalian cytosolic Fe-S protein maturation. PMID: 18270200
human IscA1 plays an important role in both mitochondrial and cytosolic iron-sulfur cluster biogenesis, and a notable component of the latter is the interaction between IscA1 and IOP1. PMID: 19864422

Protein Families

NARF family

Tissue Specificity

Widely expressed.

Database Links

HGNC: 14179

OMIM: 611118

KEGG: hsa:64428

STRING: 9606.ENSP00000251588

UniGene: Hs.513247

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Target Therapy

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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