CIAO3

CIAO3, also known as cytosolic iron-sulfur assembly component 3, is a protein involved in the iron-sulfur cluster assembly pathway. It functions as a scaffold protein, facilitating the assembly of iron - sulfur clusters which are crucial cofactors for many enzymes. This protein is associated with the ISC (Iron - Sulfur Cluster) biogenesis pathway.
Alterations in CIAO3 have been linked to certain genetic disorders related to iron - sulfur cluster metabolism. In terms of drug development, research is in the early stages. Scientists are exploring potential small - molecule compounds to target and modulate its function, with the hope of treating relevant diseases by regulating the iron - sulfur cluster assembly process.