NDUFB10 Antibody

Datasheet

Code	CSB-PA015642ESR1HU
Size	US$166
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Image	Western blot All lanes: NDUFB10 antibody at 2.42µg/ml Lane 1: Mouse brain tissue Lane 2: HepG2 whole cell lysate Lane 3: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 21 kDa Observed band size: 21 kDa Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA015642ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA015642ESR1HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) NDUFB10 Polyclonal antibody

Uniprot No.

O96000

Target Names

NDUFB10

Alternative Names

0610011B04Rik antibody; 22kDa antibody; CI PDSW antibody; CI-PDSW antibody; Complex I PDSW antibody; Complex I PDSW subunit antibody; Complex I-PDSW antibody; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 10 22kDa antibody; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 antibody; NADH ubiquinone oxidoreductase PDSW subunit antibody; NADH-ubiquinone oxidoreductase PDSW subunit antibody; NDUBA_HUMAN antibody; NDUFB 10 antibody; Ndufb10 antibody; PDSW antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 protein (1-172AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.

Gene References into Functions

findings indicate that mutations in NDUFB10 are a novel cause of complex I deficiency associated with a late stage assembly defect and emphasize the role of intermembrane space proteins for the efficient assembly of complex I. PMID: 28040730
Src kinase inhibition led to a decrease in mitochondrial respiration via a specific decrease in complex I activities which is associated with a lower phosphorylation of the complex I subunit NDUFB10. PMID: 22321370

Subcellular Location

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Protein Families

Complex I NDUFB10 subunit family

Database Links

HGNC: 7696

OMIM: 603843

KEGG: hsa:4716

STRING: 9606.ENSP00000268668

UniGene: Hs.513266

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Oxidative Phosphorylation

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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