NECAB3 Antibody

Code CSB-PA015676GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
NECAB3
Alternative Names
amyloid beta (A4) precursor protein binding; family A; member 2 binding protein antibody; Amyloid beta A4 protein binding family A member 2 binding protein antibody; Amyloid beta A4 protein-binding family A member 2-binding protein antibody; APBA2BP antibody; dJ63M2.4 antibody; dJ63M2.5 antibody; EFCBP3 antibody; N terminal EF hand calcium binding protein 3 antibody; N-terminal EF-hand calcium-binding protein 3 antibody; NECA3_HUMAN antibody; NECAB3 antibody; Nek2 interacting protein 1 antibody; Nek2-interacting protein 1 antibody; Neuronal calcium binding protein 3 antibody; Neuronal calcium-binding protein 3 antibody; NIP1 antibody; STIP3 antibody; Synaptotagmin interacting protein 2 antibody; SYTIP2 antibody; X11L binding protein 51 antibody; X11L-binding protein 51 antibody; XB51 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human NECAB3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta. May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3.
Gene References into Functions
  1. hXB51 isoforms regulate Abeta generation differently, either enhancing it by modifying the association of X11L with APP or suppressing it in an X11L-independent manner PMID: 12780348
  2. xb51 may be required for maturation and maintenance of xb51-expressing neurons in the forebrain PMID: 19035353
Subcellular Location
Golgi apparatus.
Tissue Specificity
Strongly expressed in heart and skeletal muscle, moderately in brain and pancreas.
Database Links

HGNC: 15851

OMIM: 612478

KEGG: hsa:63941

STRING: 9606.ENSP00000246190

UniGene: Hs.516986

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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