NECAB3 Antibody

Datasheet

Code	CSB-PA015676GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

Q96P71

Target Names

NECAB3

Alternative Names

amyloid beta (A4) precursor protein binding; family A; member 2 binding protein antibody; Amyloid beta A4 protein binding family A member 2 binding protein antibody; Amyloid beta A4 protein-binding family A member 2-binding protein antibody; APBA2BP antibody; dJ63M2.4 antibody; dJ63M2.5 antibody; EFCBP3 antibody; N terminal EF hand calcium binding protein 3 antibody; N-terminal EF-hand calcium-binding protein 3 antibody; NECA3_HUMAN antibody; NECAB3 antibody; Nek2 interacting protein 1 antibody; Nek2-interacting protein 1 antibody; Neuronal calcium binding protein 3 antibody; Neuronal calcium-binding protein 3 antibody; NIP1 antibody; STIP3 antibody; Synaptotagmin interacting protein 2 antibody; SYTIP2 antibody; X11L binding protein 51 antibody; X11L-binding protein 51 antibody; XB51 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human NECAB3

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta. May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3.

Gene References into Functions

hXB51 isoforms regulate Abeta generation differently, either enhancing it by modifying the association of X11L with APP or suppressing it in an X11L-independent manner PMID: 12780348
xb51 may be required for maturation and maintenance of xb51-expressing neurons in the forebrain PMID: 19035353

Subcellular Location

Golgi apparatus.

Tissue Specificity

Strongly expressed in heart and skeletal muscle, moderately in brain and pancreas.

Database Links

HGNC: 15851

OMIM: 612478

KEGG: hsa:63941

STRING: 9606.ENSP00000246190

UniGene: Hs.516986

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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