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NEUROG2 Antibody, Biotin conjugated

Datasheet
Code CSB-PA887960LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NEUROG2 Polyclonal antibody
Uniprot No.
Q9H2A3
Target Names
NEUROG2
Alternative Names
Atoh 4 antibody; Atoh4 antibody; bHLHa8 antibody; Class A basic helix-loop-helix protein 8 antibody; Math 4A antibody; Math4A antibody; MGC antibody; MGC46562 antibody; NEUROG 2 antibody; NEUROG2 antibody; Neurogenin-2 antibody; Neurogenin2 antibody; NGN 2 antibody; NGN-2 antibody; NGN2 antibody; NGN2_HUMAN antibody; Protein atonal homolog 4 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Neurogenin-2 protein (194-262AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').
Gene References into Functions
  1. Study shows neurogenin 2 enhances the generation of patient-specific induced neuronal cells. PMID: 25912433
  2. Results show that neurogenin-1 and -2 drive homogeneous differentiation of human stem cells into bipolar neurons in 4 days in defined media. PMID: 25403753
  3. human embryonic progenitors expressing neurogenin-2 stimulate axonal sprouting and improve motor recovery after severe spinal cord injury PMID: 21209909
  4. Novel compound heterozygous variants (Gly56Arg and Asp206Glu) were found in a 91-year normal male, suggesting that mutations in the coding region of the NEUROG2 gene play little or no role in the development of PD. PMID: 19879328
  5. expression of Ngn2 during the differentiation of neuronl human embryo stem cells. PMID: 17784840
  6. Rat and mouse species-dependent differences of Nurr1 and Ngn2 actions in dopamine neuron differentiation. PMID: 18242186

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Subcellular Location
Nucleus.
Database Links

HGNC: 13805

OMIM: 606624

KEGG: hsa:63973

STRING: 9606.ENSP00000317333

UniGene: Hs.744415

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