NEUROG2 Antibody, HRP conjugated

Code CSB-PA887960LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NEUROG2 Polyclonal antibody
Uniprot No.
Target Names
NEUROG2
Alternative Names
Atoh 4 antibody; Atoh4 antibody; bHLHa8 antibody; Class A basic helix-loop-helix protein 8 antibody; Math 4A antibody; Math4A antibody; MGC antibody; MGC46562 antibody; NEUROG 2 antibody; NEUROG2 antibody; Neurogenin-2 antibody; Neurogenin2 antibody; NGN 2 antibody; NGN-2 antibody; NGN2 antibody; NGN2_HUMAN antibody; Protein atonal homolog 4 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Neurogenin-2 protein (194-262AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').
Gene References into Functions
  1. Study shows neurogenin 2 enhances the generation of patient-specific induced neuronal cells. PMID: 25912433
  2. Results show that neurogenin-1 and -2 drive homogeneous differentiation of human stem cells into bipolar neurons in 4 days in defined media. PMID: 25403753
  3. human embryonic progenitors expressing neurogenin-2 stimulate axonal sprouting and improve motor recovery after severe spinal cord injury PMID: 21209909
  4. Novel compound heterozygous variants (Gly56Arg and Asp206Glu) were found in a 91-year normal male, suggesting that mutations in the coding region of the NEUROG2 gene play little or no role in the development of PD. PMID: 19879328
  5. expression of Ngn2 during the differentiation of neuronl human embryo stem cells. PMID: 17784840
  6. Rat and mouse species-dependent differences of Nurr1 and Ngn2 actions in dopamine neuron differentiation. PMID: 18242186

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Subcellular Location
Nucleus.
Database Links

HGNC: 13805

OMIM: 606624

KEGG: hsa:63973

STRING: 9606.ENSP00000317333

UniGene: Hs.744415

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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