NHLH1/NHLH2 Antibody

Code CSB-PA078343
Size US$297
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  • Western blot analysis of extracts from Jurkat cells, using HEN1/2 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NHLH1/NHLH2 Polyclonal antibody
Uniprot No.
Target Names
NHLH1/NHLH2
Alternative Names
NHLH1 antibody; BHLHA35 antibody; HEN1 antibody; Helix-loop-helix protein 1 antibody; HEN-1 antibody; Class A basic helix-loop-helix protein 35 antibody; bHLHa35 antibody; Nescient helix loop helix 1 antibody; NSCL-1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from internal of Human HEN1/2.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.
Gene References into Functions
  1. The polymorphism was further reproducibly associated with a DNA methylation signature in whole blood (P = 4.5x10-40) that also associated with allergic sensitization and expression in blood of the cytokine TSLP (P = 1.1x10-4). Knockdown of the transcription factor predicted to bind the enhancer region (NHLH1) in a human cell line (HEK293) expressing NHLH1 resulted in lower TSLP expression PMID: 27149122
  2. This study identified that CGPs was found to significantly correlate with the differential expression and methylation of genes encoding nescient helix-loop-helix 1. PMID: 25243493
  3. expression of NSCL-1 and NSCL-2 in the developing central and peripheral nervous system, most likely in developing neurons. PMID: 1328219
Subcellular Location
Nucleus.
Database Links

HGNC: 7817

OMIM: 162360

KEGG: hsa:4807

STRING: 9606.ENSP00000302189

UniGene: Hs.30956

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