NIFK Antibody

Code CSB-PA070020
Size US$100
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Product Details

Uniprot No.
Target Names
NIFK
Alternative Names
hNIFK antibody; MK67I_HUMAN antibody; MKI67 FHA Domain Interacting Nucleolar Phosphoprotein antibody; MKI67 FHA domain-interacting nucleolar phosphoprotein antibody; mki67ip antibody; NOPP34 antibody; Nucleolar phosphoprotein Nopp34 antibody; Nucleolar protein interacting with the FHA domain of pKI 67 antibody; Nucleolar protein interacting with the FHA domain of pKI-67 antibody; pKi67 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from Human NIFK around the non-phosphorylation site of T234.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
IHC, IF, ELISA
Recommended Dilution
Application Recommended Dilution
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. NIFK is required for lung cancer progression via the RUNX1-dependent CK1alpha repression, which activates TCF4/beta-catenin signaling in metastasis and the Ki-67-dependent regulation in cell proliferation. PMID: 26984280
  2. The RNA recognition motif of NIFK is required for rRNA maturation during cell cycle progression. PMID: 25826659
  3. Potential encounter complexes of the Ki67FHA receptor and hNIFK peptide are misregistered states of the beta-sheet. PMID: 21539773
  4. nmr analysis of the solution structure of the FHA domain of human Ki67 and mapping of the binding surface for NIFK binding PMID: 14659764
  5. Better basal gene expression was observed by co-cultured respiratory epithelial cells compared to dispase dissociated cells. PMID: 17891046

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Subcellular Location
Nucleus, nucleolus. Chromosome. Note=Localizes to mitotic chromosomes in conjunction with MKI67.
Database Links

HGNC: 17838

OMIM: 611970

KEGG: hsa:84365

STRING: 9606.ENSP00000285814

UniGene: Hs.367842

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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