NKX6-3 Antibody

Code CSB-PA094684
Size US$297
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  • Western blot analysis of extracts from K562 cells and COS-7 cells, using NKX6.3 antibody.
  • Immunofluorescence analysis of HUVEC cells, using NKX6.3 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NKX6-3 Polyclonal antibody
Uniprot No.
Target Names
NKX6-3
Alternative Names
FLJ25169 antibody; Homeobox protein Nkx 6.3 antibody; Homeobox protein Nkx-6.3 antibody; NK6 homeobox 3 antibody; NKX6-3 antibody; NKX6.3 antibody; NKX63 antibody; NKX63_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from internal of Human NKX6.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB,IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
IF 1:100-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Putative transcription factor, which may be involved in patterning of central nervous system and pancreas.
Gene References into Functions
  1. these results suggest that NKX6.3 inhibits ROS production by inducing the expression of Hace1 via down-regulating NF-kB and DNMT1 activity in gastric epithelial cells. PMID: 28584243
  2. The expression level of NKX6.3 is involved in regulation of gastric cancer progression and expression of Wnt/beta-catenin and Rho-GTPase pathway-related genes in clinical samples. PMID: 27333045
  3. Suggest that NKX6.3 might function as a master regulator of gastric differentiation by affecting SOX2 and CDX2 expression and the NKX6.3 inactivation may result in intestinal metaplasia in gastric epithelial cells. PMID: 26743476
  4. Data suggest that NK6 homeobox 3 (NKX6.3) may control the fate of gastric mucosal cells and function as a gastric tumor suppressor. PMID: 26314965
Subcellular Location
Nucleus.
Database Links

HGNC: 26328

OMIM: 610772

KEGG: hsa:157848

STRING: 9606.ENSP00000429553

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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