NLGN4Y Antibody

Code CSB-PA015858GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
NLGN4Y
Alternative Names
ASPGX2 antibody; AUTSX2 antibody; HGNC:14287 antibody; HLNX antibody; HNLX antibody; KIAA0951 antibody; KIAA1260 antibody; MGC22376 antibody; Neuroligin 4 X linked antibody; Neuroligin 4, Y linked antibody; Neuroligin X antibody; Neuroligin Y antibody; Neuroligin-4 antibody; NLGN antibody; NLGN4 antibody; NLGN4X antibody; NLGN4Y antibody; NLGNY_HUMAN antibody; Y-linked antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human NLGN4Y
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Putative neuronal cell surface protein involved in cell-cell-interactions.
Gene References into Functions
  1. Results suggest an association between a maternal immune response to neuroligin 4 Y-linked (NLGN4Y) and subsequent sexual orientation in male offspring. PMID: 29229842
  2. Results suggest that NLGN4Y is an important negative regulator in prostate cancer progression. PMID: 27626693
  3. Expression of NLGN4Y, a gene that may be involved in synaptic function, is increased in boys with XYY PMID: 25558953
  4. investigated 12 single-nucleotide polymorphisms in Y-linked neuroligin 4, transducin b-like 1, and eukaryotic translation initiation factor 1a genes, results suggest a Y chromosome effect in autism PMID: 19605777
  5. Neuroligin mutations most probably represent rare causes of autism; it is unlikely that the allelic variants in any of these genes would be major risk factors for autism. PMID: 16077734
  6. The coding sequences and splice junctions of the NLGN4Y gene were analyzed in 335 male samples (290 with autism and 45 with mental retardation) to analyze sequence variants in NLGN4Y that are associated with autism or mental retardation. PMID: 18628683

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Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density membrane.
Protein Families
Type-B carboxylesterase/lipase family
Tissue Specificity
Expressed in fetal and adult brain, prostate and testis.
Database Links

HGNC: 15529

OMIM: 400028

KEGG: hsa:22829

STRING: 9606.ENSP00000342535

UniGene: Hs.439199

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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