NLGN4Y Antibody

Datasheet

Code	CSB-PA818786ESR1HU
Size	US$166
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Image	Western blot All lanes: NLGN4Y antibody at 6μg/ml Lane 1: A549 whole cell lysate Lane 2: Mouse brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 93, 73, 16, 29 kDa Observed band size: 93 kDa Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA818786ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA818786ESR1HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) NLGN4Y Polyclonal antibody

Uniprot No.

Q8NFZ3

Target Names

NLGN4Y

Alternative Names

ASPGX2 antibody; AUTSX2 antibody; HGNC:14287 antibody; HLNX antibody; HNLX antibody; KIAA0951 antibody; KIAA1260 antibody; MGC22376 antibody; Neuroligin 4 X linked antibody; Neuroligin 4, Y linked antibody; Neuroligin X antibody; Neuroligin Y antibody; Neuroligin-4 antibody; NLGN antibody; NLGN4 antibody; NLGN4X antibody; NLGN4Y antibody; NLGNY_HUMAN antibody; Y-linked antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Neuroligin-4, Y-linked protein (682-816AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Putative neuronal cell surface protein involved in cell-cell-interactions.

Gene References into Functions

Results suggest an association between a maternal immune response to neuroligin 4 Y-linked (NLGN4Y) and subsequent sexual orientation in male offspring. PMID: 29229842
Results suggest that NLGN4Y is an important negative regulator in prostate cancer progression. PMID: 27626693
Expression of NLGN4Y, a gene that may be involved in synaptic function, is increased in boys with XYY PMID: 25558953
investigated 12 single-nucleotide polymorphisms in Y-linked neuroligin 4, transducin b-like 1, and eukaryotic translation initiation factor 1a genes, results suggest a Y chromosome effect in autism PMID: 19605777
Neuroligin mutations most probably represent rare causes of autism; it is unlikely that the allelic variants in any of these genes would be major risk factors for autism. PMID: 16077734
The coding sequences and splice junctions of the NLGN4Y gene were analyzed in 335 male samples (290 with autism and 45 with mental retardation) to analyze sequence variants in NLGN4Y that are associated with autism or mental retardation. PMID: 18628683

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Subcellular Location

Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density membrane.

Protein Families

Type-B carboxylesterase/lipase family

Tissue Specificity

Expressed in fetal and adult brain, prostate and testis.

Database Links

HGNC: 15529

OMIM: 400028

KEGG: hsa:22829

STRING: 9606.ENSP00000342535

UniGene: Hs.439199

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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