NMB Antibody

Code CSB-PA015880GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
NMB
Alternative Names
NMB antibody; Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B] antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human NMB
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Stimulates smooth muscle contraction in a manner similar to that of bombesin.
Gene References into Functions
  1. Genetic clues to the mechanism by which MC4R, FTO, and NMB influences changes in BMI and obesity. PMID: 27634552
  2. Rs2292462 was associated with left ventricular hypertrophy in type 2 diabetic patients. PMID: 23879873
  3. There was no association between eating behaviour traits, or anthropometric variables, and NMB p.P73T polymorphism. PMID: 21527296
  4. TT genotype of the NMB rs3809508 polymorphism was associated with a higher risk of obesity and moreover, the effects of this polymorphism on anthropometric values were influenced by the maternal educational level. PMID: 20010906
  5. lysosomal degradation of neuromedin B is dependent on tripeptidyl peptidase-I PMID: 15158442
  6. NMB and its receptor are coexpressed by proliferating cells in which they act in an autocrine fashion with similar and modest potency in both normal and malignant colonic epithelial cells. PMID: 15528253
  7. Associated with eating behaviors PMID: 15585758
  8. REsults describe the expression of neuromedin B in adipose tissue and its regulation by changes in energy balance. PMID: 17766645
  9. No significant differences in the genotype distribution were demonstrated between normal weight and overweight/obese subjects PMID: 18271693

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Subcellular Location
Secreted.
Protein Families
Bombesin/neuromedin-B/ranatensin family
Database Links

HGNC: 7842

OMIM: 162340

KEGG: hsa:4828

STRING: 9606.ENSP00000378089

UniGene: Hs.386470

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