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NOMO1 Antibody, Biotin conjugated

Datasheet
Code CSB-PA015931LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NOMO1 Polyclonal antibody
Uniprot No.
Q15155
Target Names
NOMO1
Alternative Names
Nodal modulator 1 antibody; NOMO 1 antibody; Nomo antibody; NOMO1 antibody; NOMO1_HUMAN antibody; PM5 antibody; pM5 protein antibody; pM5 protein telomeric copy antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Nodal modulator 1 protein (918-1044AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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NOMO1 Antibodies

NOMO1 Proteins

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Target Background

Function
Component of a ribosome-associated endoplasmic reticulum (ER) translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis. May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning, via its interaction with NCLN/Nicalin.
Gene References into Functions
  1. Microsatellite-Stable (MSS) CRC showed a very high proportion of homozygous loss of NOMO1 (54 of 59 cases, 91.5%), while the deletion was observed in only 7 out of 16 MSI cases. Deletion of NOMO1 is a molecular marker predominantly associated with CRC, particularly MSS subtypes. PMID: 28416736
  2. H19 gene could inhibit human trophoblast cell proliferation via encoding miR-675 that targeted NOMO1 downregulation. PMID: 22832245
Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein.
Tissue Specificity
Expressed in colon tumor tissue and in adjacent normal colonic mucosa.
Database Links

HGNC: 30060

OMIM: 609157

KEGG: hsa:23420

STRING: 9606.ENSP00000287667

UniGene: Hs.743963

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