NOMO1 Antibody

Code CSB-PA015931GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
NOMO1
Alternative Names
Nodal modulator 1 antibody; NOMO 1 antibody; Nomo antibody; NOMO1 antibody; NOMO1_HUMAN antibody; PM5 antibody; pM5 protein antibody; pM5 protein telomeric copy antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human NOMO1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of a ribosome-associated endoplasmic reticulum (ER) translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis. May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning, via its interaction with NCLN/Nicalin.
Gene References into Functions
  1. Microsatellite-Stable (MSS) CRC showed a very high proportion of homozygous loss of NOMO1 (54 of 59 cases, 91.5%), while the deletion was observed in only 7 out of 16 MSI cases. Deletion of NOMO1 is a molecular marker predominantly associated with CRC, particularly MSS subtypes. PMID: 28416736
  2. H19 gene could inhibit human trophoblast cell proliferation via encoding miR-675 that targeted NOMO1 downregulation. PMID: 22832245
Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein.
Tissue Specificity
Expressed in colon tumor tissue and in adjacent normal colonic mucosa.
Database Links

HGNC: 30060

OMIM: 609157

KEGG: hsa:23420

STRING: 9606.ENSP00000287667

UniGene: Hs.743963

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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