NOP2 Antibody

Code CSB-PA015938GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
NOP2
Alternative Names
NOP2 antibody; NOL1 antibody; NSUN1Probable 28S rRNA antibody; cytosine(4447)-C(5))-methyltransferase antibody; EC 2.1.1.- antibody; Nucleolar protein 1 antibody; Nucleolar protein 2 homolog antibody; Proliferating-cell nucleolar antigen p120 antibody; Proliferation-associated nucleolar protein p120 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human NOP2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in ribosomal large subunit assembly. S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA (Probable). May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation (Probable).
Gene References into Functions
  1. NOL1 represents a new route by which telomerase activates transcription of cyclin D1 gene, thus maintaining cell proliferation capacity PMID: 26906424
  2. p120 has an rRNA:5-Methylcytosine-Methyltransferase activity. PMID: 26196125
  3. Findings suggest a newly discovered role of Nop2 in both mature neurons and in cells possibly involved in the regeneration of nervous tissue PMID: 25481415
Subcellular Location
Nucleus, nucleolus.
Protein Families
Class I-like SAM-binding methyltransferase superfamily, RsmB/NOP family
Database Links

HGNC: 7867

OMIM: 164031

KEGG: hsa:4839

STRING: 9606.ENSP00000382392

UniGene: Hs.534334

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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