NRBP1 Antibody

1. Study have identified a gout risk gene, NRBP1,and demonstrated that increased NRBP1 expression in gout patients may be regulated through methylation-dependent binding of TFAP2A to the B1 region, a 72 bp upstream of NRBP1 transcription start site. PMID: 28932319
2. The present study deals with the molecular modeling of the viral protein (NS3 of DENV1-4), the host protein (NRBP) and their interactions through protein-protein docking study. PMID: 24910013
3. Targeting this we performed homology modeling and protein-protein docking study of NS3 with NRBP (Nuclear Receptor Binding Protein) of human as it has been proved that NS3 of DENV interacts with NRBP which causes cellular trafficking in human cell. PMID: 24372240
4. High NRBP1 expression in prostate cancer is linked with poor clinical outcomes and increased cancer cell growth. PMID: 22473923
5. It was shown that NRBP1 is a tumour suppressor that plays a critical role in intestinal cell homoeostasis. NRBP1 levels are reduced in a wide variety of human tumours. Reduced NRBP1 levels in lung cancer correlates with a poor prognosis. PMID: 22510880
6. Interaction of the small GTPase Rac3 with NRBP: results suggest that NRBP functions in subcellular trafficking and may be directed to specific subcellular locations through interaction with small GTPases of the Rho family PMID: 11956649
7. mediates phosphorylation of the 14-3-3 binding site of myeloid leukemia factor 1 PMID: 12176995
8. NS3 protein of dengue virus type 2 interacted specifically with nuclear receptor binding protein, a host cellular protein that influences trafficking between the endoplasmic reticulum and Golgi, and that interacts with Rac3 PMID: 15084397

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HGNC: 7993

OMIM: 606010

KEGG: hsa:29959

STRING: 9606.ENSP00000233557

UniGene: Hs.515876