NREP Antibody

1. P311 is a novel TGFbeta1/Smad signaling-mediated regulator of transdifferentiation in epidermal stem cells during cutaneous wound healing. PMID: 27906099
2. P311 could accelerate skin wound reepithelialization by promoting the migration of Epidermal Stem Cell through RhoA and Rac1 activation. PMID: 27927130
3. These studies demonstrate that P311 is required for the production of normal cutaneous scars PMID: 27939132
4. P311 plays a key role in renal fibrosis via TGFbeta1/Smad signaling, which could be a novel target for the management of renal fibrosis. PMID: 26616407
5. P311 may promote the migration of ESCs both in micewith superficial partial-thickness burns and in an injured cell model in vitro, and it may play an important role in wound healing. PMID: 22967977
6. Protein HYI may closely bind with protein P311 by an alpha helix in hypertrophic scar fibroblasts. PMID: 22490543
7. P311 and ITGB4BP expression was elevated in non-small cell lung cancer, possibly indicative of a new signaling pathway. PMID: 21029697
8. P311 may be involved in the pathogenesis of hypertrophic scar via induction of a myofibrobla PMID: 20404911
9. role for P311 in inducing TGF-beta1-independent myofibroblast transformation PMID: 12417574
10. These results suggest a role for levels of P311 in regulating glioma motility and invasion through the reorganization of actin cytoskeleton at the cell periphery. PMID: 16229809
11. P311 expression is tightly regulated during the critical periods of alveolar formation, and that under pathologic conditions, its relative absence may contribute to failure of alveolar regeneration and lead to the development of human emphysema. PMID: 16484684

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HGNC: 16834

OMIM: 607332

KEGG: hsa:9315

UniGene: Hs.36053