NUFIP1 Antibody

Code CSB-PA016182GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
NUFIP1
Alternative Names
NUFIP1 antibody; Nuclear fragile X mental retardation-interacting protein 1 antibody; Nuclear FMRP-interacting protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human NUFIP1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Binds RNA.
Gene References into Functions
  1. NUFIP1 is a receptor for the selective autophagy of ribosomes. PMID: 29700228
  2. Results solve the structure of a complex resulting from interaction between protein fragments of human NUFIP1 and its cofactor ZNHIT3, and emphasize their imbrication. Also, it seems that the complexes involving NUFIP1, ZNHIT3, and SNU13 share strong structural similarities between human and yeast, suggesting that the initial steps of the box C/D snoRNP assembly process are conserved among species. PMID: 27594683
  3. NUFIP is associated with preinitiation complexes, open transcription complexes, and elongation complexes and facilitates ATP-dependent dissociation of hyperphosphorylated pol II from open transcription complexes in vitro PMID: 15107825
Subcellular Location
Nucleus. Note=Distributed in the nucleus in a dot-like pattern.
Tissue Specificity
Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.
Database Links

HGNC: 8057

OMIM: 604354

KEGG: hsa:26747

STRING: 9606.ENSP00000368459

UniGene: Hs.525006

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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