NUGGC Antibody, Biotin conjugated

Code CSB-PA718072LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NUGGC Polyclonal antibody
Uniprot No.
Target Names
NUGGC
Alternative Names
NUGGC antibody; C8orf80 antibody; HMFN0672 antibody; Nuclear GTPase SLIP-GC antibody; EC 3.6.1.- antibody; Speckled-like pattern in the germinal center antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Nuclear GTPase SLIP-GC protein (1-228AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA. Reduces somatic hypermutation in B-cells which may enhance genome stability.
Gene References into Functions
  1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  2. SLIP-GC is a replication-related protein in germinal center B cells whose reduction is toxic to cells through an AICDA-dependent mechanism. PMID: 19734146
Subcellular Location
Nucleus speckle.
Tissue Specificity
Expressed in germinal center B-cell and in lymphomas derived from germinal center B-cell.
Database Links

HGNC: 33550

KEGG: hsa:389643

UniGene: Hs.370129

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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