NUGGC Antibody, FITC conjugated

Code CSB-PA718072LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NUGGC Polyclonal antibody
Uniprot No.
Target Names
NUGGC
Alternative Names
NUGGC antibody; C8orf80 antibody; HMFN0672 antibody; Nuclear GTPase SLIP-GC antibody; EC 3.6.1.- antibody; Speckled-like pattern in the germinal center antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Nuclear GTPase SLIP-GC protein (1-228AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA. Reduces somatic hypermutation in B-cells which may enhance genome stability.
Gene References into Functions
  1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  2. SLIP-GC is a replication-related protein in germinal center B cells whose reduction is toxic to cells through an AICDA-dependent mechanism. PMID: 19734146
Subcellular Location
Nucleus speckle.
Tissue Specificity
Expressed in germinal center B-cell and in lymphomas derived from germinal center B-cell.
Database Links

HGNC: 33550

KEGG: hsa:389643

UniGene: Hs.370129

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