OLFM1 Antibody, FITC conjugated

Datasheet

Code	CSB-PA858725LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) OLFM1 Polyclonal antibody

Uniprot No.

Q99784

Target Names

OLFM1

Alternative Names

AMY antibody; NEUROBLASTOMA PROTEIN antibody; Neuronal olfactomedin-related ER localized protein antibody; Noe1 antibody; NOE1_HUMAN antibody; Noel antibody; Noel1 antibody; Noelin antibody; Noelin1 antibody; OlfA antibody; Olfactomedin 1 antibody; Olfactomedin-1 antibody; Olfm1 antibody; Pancortin 1 antibody; Pancortin antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Noelin protein (374-441AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Contributes to the regulation of axonal growth in the embryonic and adult central nervous system by inhibiting interactions between RTN4R and LINGO1. Inhibits RTN4R-mediated axon growth cone collapse. May play an important role in regulating the production of neural crest cells by the neural tube. May be required for normal responses to olfactory stimuli.

Gene References into Functions

OLFM1 is a negative regulator of non-canonical NF-kappaB signalling by interacting with and inhibiting NIK. Thus, OLFM1 may serve as a valuable biomarker and therapeutic target for colorectal cancer (CRC) patients. PMID: 27555280
human chorionic gonadotropin stimulated miR-212, which down-regulated OLFM1 and CTBP1 expression in fallopian and endometrial epithelial cells to favor spheroid attachment PMID: 26377223
OLF domains from H. sapiens olfactomedin-1 and M. musculus gliomedin were biophysically, biochemically, and structurally characterized. PMID: 26121352
Down-regulation of OLFM1 in fallopian tube epithelial cells enhances spheroid attachment to fallopian tube. PMID: 25999259
Wnt activation suppresses Olfm-1 expression, and this may predispose a favorable microenvironment of the retained embryo in the Fallopian tube, leading to ectopic pregnancy in humans PMID: 21968811

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Subcellular Location

Secreted. Cell junction, synapse. Endoplasmic reticulum. Cell projection, axon. Perikaryon.

Database Links

HGNC: 17187

OMIM: 605366

KEGG: hsa:10439

STRING: 9606.ENSP00000252854

UniGene: Hs.522484

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Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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