OLFML3 Antibody, Biotin conjugated

Code CSB-PA885708LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) OLFML3 Polyclonal antibody
Uniprot No.
Target Names
OLFML3
Alternative Names
HNOEL-iso antibody; hOLF44 antibody; OLF44 antibody; Olfactomedin like 3 antibody; Olfactomedin-like protein 3 antibody; OLFL3_HUMAN antibody; OLFML3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Olfactomedin-like protein 3 protein (201-406AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation. May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.
Gene References into Functions
  1. This paper reports OLFML3 expression in human and baboon eye. The full coding DNA sequence has 1221 bp, from which an open reading frame of 406 amino acid was obtained. PMID: 23398349
  2. may have matrix-related function involved in human placental and embryonic development, or play a similar role in other physiological processes PMID: 15280020
Subcellular Location
Secreted.
Protein Families
OLFML3 family
Tissue Specificity
Abundant in placenta, moderate in liver and heart, whereas fairly weak in other tissues examined. On term placenta, mainly localized extracellularly surrounding the syncytiotrophoblastic cells and very rarely expressed in the maternal decidua layer.
Database Links

HGNC: 24956

OMIM: 610088

KEGG: hsa:56944

UniGene: Hs.9315

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