OTOP1 Antibody, FITC conjugated

Code CSB-PA752530LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) OTOP1 Polyclonal antibody
Uniprot No.
Target Names
OTOP1
Alternative Names
OTOP1 antibody; Proton channel OTOP1 antibody; Otopetrin-1 antibody; hOtop1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Proton channel OTOP1 protein (414-544AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Proton-selective channel that specifically transports protons into cells. Proton channel activity is only weakly-sensitive to voltage. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration. Probably acts by maintaining the pH appropriate for formation of otoconia. Regulates purinergic control of intracellular calcium in vestibular supporting cells. May be involved in sour taste perception in sour taste cells by mediating entry of protons within the cytosol. Also involved in energy metabolism, by reducing adipose tissue inflammation and protecting from obesity-induced metabolic dysfunction.
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
Otopetrin family
Database Links

HGNC: 19656

OMIM: 607806

KEGG: hsa:133060

STRING: 9606.ENSP00000296358

UniGene: Hs.534544

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