OTUD6B Antibody

Code CSB-PA847646LA01HU
Size US$166
Order now
Image
  • Western blot
    All lanes: OTUD6B antibody at 4µg/ml
    Lane 1: PC-3 whole cell lysate
    Lane 2: 293T whole cell lysate
    Lane 3: MDA-MB-231 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 34, 22 kDa
    Observed band size: 34 kDa

  • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA847646LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA847646LA01HU at dilution of 1:100

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) OTUD6B Polyclonal antibody
Uniprot No.
Target Names
OTUD6B
Alternative Names
CGI-77 antibody; DUBA-5 antibody; DUBA5 antibody; OTU domain containing protein 6B antibody; OTU domain-containing protein 6B antibody; OTU6B_HUMAN antibody; OTUD6B antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Deubiquitinase OTUD6B protein (1-293AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The OTUD6B Antibody (Product code: CSB-PA847646LA01HU) is Non-conjugated. For OTUD6B Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA847646LB01HU OTUD6B Antibody, HRP conjugated ELISA
FITC CSB-PA847646LC01HU OTUD6B Antibody, FITC conjugated
Biotin CSB-PA847646LD01HU OTUD6B Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Deubiquitinating enzyme that may play a role in the ubiquitin-dependent regulation of protein synthesis, downstream of mTORC1. May associate with the protein synthesis initiation complex and modify its ubiquitination to repress translation. May also repress DNA synthesis and modify different cellular targets thereby regulating cell growth and proliferation. May also play a role in proteasome assembly and function.; Stimulates protein synthesis. Influences the expression of CCND1/cyclin D1 by promoting its translation and regulates MYC/c-Myc protein stability.
Gene References into Functions
  1. The global OTUD6B expression level does not change significantly between nonneoplastic and malignant tissues, suggesting that modifications of splicing factors during the process of transformation are responsible for this isoform switch. PMID: 27864334
  2. OTUD6B encodes a deubiquitinating enzyme; study reports biallelic pathogenic variants in OTUD6B in 12 individuals from 6 families with intellectual disability syndrome associated with seizures & dysmorphic features; other features include developmental delay, microcephaly, absent speech, hypotonia, growth retardation, feeding difficulties, structural brain abnormalities, malformations of heart & musculoskeleton. PMID: 28343629
  3. down-regulation of Otud-6b expression after prolonged cytokine stimulation may be required for cell proliferation in B lymphocytes PMID: 21267069
Database Links

HGNC: 24281

OMIM: 612021

KEGG: hsa:51633

STRING: 9606.ENSP00000285420

UniGene: Hs.30532

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*