P Antibody

Datasheet
Code CSB-PA303154LA01RAH
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Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P69480
Image
  • Western blot
    All lanes: P antibody at 2µg/ml
    Lane 1: Rabies virus Phosphoprotein protein at 1µg
    Lane 2: Rabies virus Phosphoprotein protein at 0.1µg
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 34, 32, 28, 26, 25 kDa
    Observed band size: 34 kDa
Immunogen Recombinant Rabies virus Phosphoprotein protein (1-297AA)
Raised in Rabbit
Species Reactivity Rabies virus
Tested Applications ELISA, WB; Recommended dilution: WB:1:1000-1:5000
Relevance Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus. Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Phosphoprotein (Protein P) (Protein M1), P
Immunogen Species Rabies virus
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Research Area Others
Target Names P
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus. Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body (By similarity).
Subcellular Location Phosphoprotein: Virion, Host cytoplasm, SUBCELLULAR LOCATION: Isoform P2: Host cytoplasm, SUBCELLULAR LOCATION: Isoform P3: Host nucleus, SUBCELLULAR LOCATION: Isoform P4: Host nucleus, SUBCELLULAR LOCATION: Isoform P5: Host nucleus
Protein Families Lyssavirus protein P family

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