PACSIN3 Antibody

Code CSB-PA892456LA01HU
Size US$166
Order now
Image
  • Western Blot
    Positive WB detected in: Rat liver tissue
    All lanes: PACSIN3 antibody at 2.7μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 49 kDa
    Observed band size: 49 kDa

  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA892456LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA892456LA01HU at dilution of 1:100

  • Immunofluorescence staining of HepG2 cells with CSB-PA892456LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

  • Western Blot
    Positive WB detected in: MCF-7 whole cell lysate, PC-3 whole cell lysate, Mouse liver tissue
    All lanes: PACSIN3 antibody at 1:2000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 49 kDa
    Observed band size: 49 kDa

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PACSIN3 Polyclonal antibody
Uniprot No.
Target Names
PACSIN3
Alternative Names
Endophilin 1 antibody; Endophilin I antibody; FLJ17861 antibody; OTTHUMP00000234262 antibody; OTTHUMP00000234263 antibody; OTTHUMP00000234264 antibody; PACN3_HUMAN antibody; Pacsin3 antibody; Protein kinase C and casein kinase substrate in neurons 3 antibody; Protein kinase C and casein kinase substrate in neurons protein 3 antibody; SDPIII antibody; SH3 domain containing protein 6511 antibody; SH3 domain-containing protein 6511 antibody; syndapin III antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Human Protein kinase C and casein kinase substrate in neurons protein 3 protein (1-300AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PACSIN3 Antibody (Product code: CSB-PA892456LA01HU) is Non-conjugated. For PACSIN3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA892456LB01HU PACSIN3 Antibody, HRP conjugated ELISA
FITC CSB-PA892456LC01HU PACSIN3 Antibody, FITC conjugated
Biotin CSB-PA892456LD01HU PACSIN3 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
IF 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity.
Gene References into Functions
  1. Show that in neuroendocrine chromaffin cells fusion pore expansion and catecholamine release are limited specifically by mutation of syndapin 3. PMID: 24500282
  2. Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules PMID: 22573331
  3. PACSIN3 has a novel function as an up-regulator in the signaling of proHB-EGF shedding induced by TPA and angiotensin II PMID: 12952982
  4. PACSIN 3 acts as an auxiliary protein of TRPV4 channel that not only affects the channel's subcellular localization but also modulates its function in a stimulus-specific manner. PMID: 18174177
Subcellular Location
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein Families
PACSIN family
Tissue Specificity
Widely expressed, with highest levels in heart and skeletal muscle, intermediate levels in placenta, liver and pancreas, and very low levels in brain, lung and kidney.
Database Links

HGNC: 8572

OMIM: 606513

KEGG: hsa:29763

STRING: 9606.ENSP00000298838

UniGene: Hs.334639

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*