PAFAH1B2 Antibody

Code CSB-PA017384LA01HU
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
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  • Immunofluorescent analysis of MCF-7 cells using CSB-PA017384LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Immunohistochemistry analysis of human colon cancer using CSB-PA017384LA01HU at dilution of 1:100

  • Immunohistochemistry analysis of human glioma using CSB-PA017384LA01HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) PAFAH1B2 Polyclonal antibody
Uniprot No. P68402
Target Names PAFAH1B2
Alternative Names Intracellular platelet activating factor acetylhydrolase alpha 2 subunit antibody; PA1B2_HUMAN antibody; PAF acetylhydrolase 30 kDa subunit antibody; PAF AH 30 kDa subunit antibody; PAF AH beta subunit antibody; PAF AH subunit beta antibody; PAF-AH 30 kDa subunit antibody; PAF-AH subunit beta antibody; PAFAH 30 kDa subunit antibody; PAFAH beta subunit antibody; PAFAH subunit beta antibody; Pafah1b2 antibody; PAFAH1B2 protein antibody; PAFAHB antibody; Platelet activating factor acetylhydrolase 1b catalytic subunit 2 antibody; Platelet activating factor acetylhydrolase IB beta subunit antibody; Platelet activating factor acetylhydrolase IB subunit beta antibody; Platelet activating factor acetylhydrolase isoform Ib beta subunit antibody; Platelet activating factor acetylhydrolase isoform Ib subunit 2 antibody; Platelet-activating factor acetylhydrolase IB subunit beta antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Platelet-activating factor acetylhydrolase IB subunit beta protein (2-229AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit.
Gene References into Functions
  1. PAF is demonstrated to be the key indicator in the lipid metabolism of polypoidal choroidal vasculopathy patients in this study. PMID: 27910906
  2. PAFAH1B2 and 1B3 are important in maintaining cancer pathogenicity across a wide spectrum of cancer types. PMID: 25945974
  3. The R92H and I198T polymorphisms are highly related to the plasma PAF-AH levels and the risk of coronary heart disease, especially among patients with blood stasis syndrome. PMID: 25034894
  4. aspirin is hydrolyzed in plasma by two enzymes, BChE and a new extracellular form of platelet-activating factor acetylhydrolase, PAFAH1b2. PMID: 23508960
  5. Knockdown of PAFAH1B2 strongly reduced Abeta secretion from human cells, and this effect was confirmed in primary cells derived from PAFAH1B2 knock-out mice PMID: 23238734
  6. Plasma PAF-AH can hydrolyze oxidized phospholipids, and may attenuate the spreading of lipid peroxidation and participate in defense mechanisms against vasospasm after aneurysmal subarachnoid hemorrhage. PMID: 21866060
  7. intracellular type I PAF acetylhydrolase (PAFAH1B2 and PAFAH1B3) is the major aspirin hydrolase of human blood PMID: 21844189
  8. PAFAH1B2 is not the gene responsible for the linkage evidence on chromosome 11q23 in protein C deficiency. PMID: 17849047
  9. splice variants of the Pafah1b2 gene transcript retain exons 1-5 and replace exon 6 with alternative exons derived from genomic sequence 3' to exon 6. Splice variants encode two proteins with different novel carboxy termini PMID: 18155631

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Subcellular Location Cytoplasm
Protein Families 'GDSL' lipolytic enzyme family, Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily
Tissue Specificity Ubiquitous.
Database Links

HGNC: 8575

OMIM: 602508

KEGG: hsa:5049

STRING: 9606.ENSP00000435289

UniGene: Hs.728488

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