PAFAH1B3 Antibody, FITC conjugated

Datasheet

Code	CSB-PA619963LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PAFAH1B3 Polyclonal antibody

Uniprot No.

Q15102

Target Names

PAFAH1B3

Alternative Names

PA1B3_HUMAN antibody; PAF acetylhydrolase 29 kDa subunit antibody; PAF AH 29 kDa subunit antibody; PAF AH subunit gamma antibody; PAF-AH 29 kDa subunit antibody; PAF-AH subunit gamma antibody; PAFAH subunit gamma antibody; Pafah1b3 antibody; PAFAHG antibody; Platelet activating factor acetylhydrolase IB subunit gamma antibody; Platelet activating factor acetylhydrolase isoform Ib gamma subunit (29kD) antibody; Platelet activating factor acetylhydrolase isoform Ib gamma subunit 29kDa antibody; Platelet activating factor acetylhydrolase isoform Ib gamma subunit antibody; Platelet-activating factor acetylhydrolase IB subunit gamma antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Platelet-activating factor acetylhydrolase IB subunit gamma protein (103-187AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Alpha1 catalytic subunit of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)) heterotetrameric enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and modulates the action of PAF. The activity and substrate specificity of PAF-AH (I) are affected by its subunit composition. Both alpha1/alpha1 homodimer (PAFAH1B3/PAFAH1B3 homodimer) and alpha1/alpha2 heterodimer(PAFAH1B3/PAFAH1B2 heterodimer) hydrolyze 1-O-alkyl-2-acetyl-sn-glycero-3-phosphoric acid (AAGPA) more efficiently than PAF, but they have little hydrolytic activity towards 1-O-alkyl-2-acetyl-sn-glycero-3-phosphorylethanolamine (AAGPE). Plays an important role during the development of brain.

Gene References into Functions

PAFAH1B3 as a critical metabolic node in breast cancer PMID: 24954006
PAFAH1B3 has been found to be differentially methylated in head and neck squamous cell carcinoma. PMID: 22461910

Subcellular Location

Cytoplasm.

Protein Families

'GDSL' lipolytic enzyme family, Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily

Tissue Specificity

In the adult, expressed in brain, skeletal muscle, kidney, thymus, spleen, colon, testis, ovary and peripheral blood leukocytes. In the fetus, highest expression occurs in brain.

Database Links

HGNC: 8576

OMIM: 603074

KEGG: hsa:5050

STRING: 9606.ENSP00000262890

UniGene: Hs.466831

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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