PAM16 Antibody

Code CSB-PA896711DA01HU
Size US$166
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Image
  • Western blot
    All lanes: PAM16 antibody at 2μg/ml
    Lane 1: HL60 whole cell lysate
    Lane 2: HepG2 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 14 kDa
    Observed band size: 14 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PAM16 Polyclonal antibody
Uniprot No.
Target Names
PAM16
Alternative Names
CGI-136 antibody; MAGMAS antibody; Magmas like protein antibody; Mitochondria associated protein involved in granulocyte macrophage colony stimulating factor signal transduction antibody; Mitochondria-associated granulocyte macrophage CSF-signaling molecule antibody; Mitochondrial import inner membrane translocase subunit TIM16 antibody; PAM16 antibody; Presequence translocase-associated motor 16 homolog (S. cerevisiae) antibody; Presequence translocated-associated motor subunit PAM16 antibody; TIM16 antibody; TIM16_HUMAN antibody; TIMM16 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Mitochondrial import inner membrane translocase subunit TIM16 protein (1-125AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PAM16 Antibody (Product code: CSB-PA896711DA01HU) is Non-conjugated. For PAM16 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA896711DB01HU PAM16 Antibody, HRP conjugated ELISA
FITC CSB-PA896711DC01HU PAM16 Antibody, FITC conjugated
Biotin CSB-PA896711DD01HU PAM16 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Regulates ATP-dependent protein translocation into the mitochondrial matrix. Inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity.
Gene References into Functions
  1. A novel essential role of Magmas is a 'ROS regulatory protein' in the maintenance of cellular redox homeostasis and imparting cytoprotection under oxidative stress. PMID: 25165880
  2. finding of deleterious MAGMAS mutations in an early lethal skeletal dysplasia supports a key role for this mitochondrial protein in the ossification process PMID: 24786642
  3. Magmas protects pituitary cells from apoptosis, suggesting its possible involvement in neoplastic transformation. PMID: 20719856
  4. Magmas expression in prostate cancer. PMID: 15704001
Involvement in disease
Spondylometaphyseal dysplasia, Megarbane-Dagher-Melike type (SMDMDM)
Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein Families
TIM16/PAM16 family
Tissue Specificity
Ubiquitously expressed.
Database Links

HGNC: 29679

OMIM: 613320

KEGG: hsa:51025

STRING: 9606.ENSP00000315693

UniGene: Hs.730693

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