PAM16 Antibody

Datasheet

Code	CSB-PA896711DA01HU
Size	US$166
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Image	Western blot All lanes: PAM16 antibody at 2μg/ml Lane 1: HL60 whole cell lysate Lane 2: HepG2 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 14 kDa Observed band size: 14 kDa
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PAM16 Polyclonal antibody

Uniprot No.

Q9Y3D7

Target Names

PAM16

Alternative Names

CGI-136 antibody; MAGMAS antibody; Magmas like protein antibody; Mitochondria associated protein involved in granulocyte macrophage colony stimulating factor signal transduction antibody; Mitochondria-associated granulocyte macrophage CSF-signaling molecule antibody; Mitochondrial import inner membrane translocase subunit TIM16 antibody; PAM16 antibody; Presequence translocase-associated motor 16 homolog (S. cerevisiae) antibody; Presequence translocated-associated motor subunit PAM16 antibody; TIM16 antibody; TIM16_HUMAN antibody; TIMM16 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Mitochondrial import inner membrane translocase subunit TIM16 protein (1-125AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The PAM16 Antibody (Product code: CSB-PA896711DA01HU) is Non-conjugated. For PAM16 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA896711DB01HU	PAM16 Antibody, HRP conjugated	ELISA
FITC	CSB-PA896711DC01HU	PAM16 Antibody, FITC conjugated
Biotin	CSB-PA896711DD01HU	PAM16 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Regulates ATP-dependent protein translocation into the mitochondrial matrix. Inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity.

Gene References into Functions

A novel essential role of Magmas is a 'ROS regulatory protein' in the maintenance of cellular redox homeostasis and imparting cytoprotection under oxidative stress. PMID: 25165880
finding of deleterious MAGMAS mutations in an early lethal skeletal dysplasia supports a key role for this mitochondrial protein in the ossification process PMID: 24786642
Magmas protects pituitary cells from apoptosis, suggesting its possible involvement in neoplastic transformation. PMID: 20719856
Magmas expression in prostate cancer. PMID: 15704001

Involvement in disease

Spondylometaphyseal dysplasia, Megarbane-Dagher-Melike type (SMDMDM)

Subcellular Location

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Protein Families

TIM16/PAM16 family

Tissue Specificity

Ubiquitously expressed.

Database Links

HGNC: 29679

OMIM: 613320

KEGG: hsa:51025

STRING: 9606.ENSP00000315693

UniGene: Hs.730693

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The Overview of Organelles Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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