PARP4 Antibody

Code CSB-PA947926
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA947926(PARP4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA947926(PARP4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
Alternative Names
PARP4 antibody; ADPRTL1 antibody; KIAA0177 antibody; PARPL antibody; Protein mono-ADP-ribosyltransferase PARP4 antibody; EC 2.4.2.- antibody; 193 kDa vault protein antibody; ADP-ribosyltransferase diphtheria toxin-like 4 antibody; ARTD4 antibody; PARP-related/IalphaI-related H5/proline-rich antibody; PH5P antibody; Poly [ADP-ribose] polymerase 4 antibody; PARP-4 antibody; Vault poly(ADP-ribose) polymerase antibody; VPARP antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide of Human PARP4
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.
Gene References into Functions
  1. Major vault protein is important in the drug resistance of cancer cells, but it requires the presence of vPARP for full activity PMID: 28551640
  2. PARP4 is a possible susceptibility gene of primary thyroid and breast cancer PMID: 26699384
  3. the protein levels of MVP, TEP1 and vPARP are actually increased in the highergrade tumors suggesting existence of post-transcriptional regulation of vault component production. PMID: 23739867
  4. REVIEW:recent findings suggesting that PARP-1 participates in DNA damage signaling in cell death PMID: 12829019
Subcellular Location
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle.
Tissue Specificity
Widely expressed; the highest levels are in the kidney; also detected in heart, placenta, lung, liver, skeletal muscle, spleen, leukocytes and pancreas.
Database Links

HGNC: 271

OMIM: 607519

KEGG: hsa:143

STRING: 9606.ENSP00000371419

UniGene: Hs.744855

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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