PCDH11X Antibody, Biotin conjugated

1. PCDH11X, expressed in brain is implicated in cell-cell communication, verbal ability, cerebral asymmetry, and dendritic synaptic plasticity, may be regarded as a new candidate gene for dyslexia. PMID: 24591081
2. PCDH11X expression was detected in the fetal neocortex, ganglionic eminences, cerebellum, and inferior olive. In the adult brain, the cerebral cortex, hippocampal formation, and cerebellum and brain stem were immunoreactive. PMID: 22744706
3. the PCDH11X/Y gene pair determines cerebral asymmetry by initiating the right shift in Homo sapiens PMID: 23600975
4. our data...failed to confirm the association between PCDH11X polymorphisms and late-onset Alzheimer's disease PMID: 21276771
5. An association between late-onset Alzheimer disease and the PCDH11X polymorphisms, was not detected. PMID: 20523261
6. PCDH11X gene polymorphism does not play a major role in the genetic predisposition to late-onset Alzheimer disease in this Han Chinese population. PMID: 20707987
7. association not found for rs5984894 polymorphism in PCDH11X in Alzheimer's disease in Italy PMID: 20555150
8. The present article investigated the patterns of alternative splicing and expression of the PCDH11X/Y genes. PMID: 19859901
9. By confirming the suspected lack of X-Y homologous status for PCDH11 in non-human primates, our results reinforce the hypothesis of a hominid-specific role for this gene in brain development PMID: 16825765
10. We consider that a stronger case can be mounted for the Protocadherin11X/Y gene pair located in the hominid specific Xq21.3/Yp11.2 region of homology that was generated by a duplication from the X PMID: 19125366
11. Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease. PMID: 19136949
12. This paper proposes that the PCDH11X/Y gene pair generates epigenetic diversity relating to the species capacity for language including predisposition to psychosis. PMID: 18502103
13. a candidate for the evolution of hominid-specific characteristics including the sexual dimorphism of cerebral asymmetry, a putative correlate of language PMID: 16874762

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HGNC: 8656

OMIM: 300246

KEGG: hsa:27328

STRING: 9606.ENSP00000362186

UniGene: Hs.655673