PCDH7 Antibody

Code CSB-PA017536LA01HU
Size US$166
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Image
  • IHC image of CSB-PA017536LA01HU diluted at 1:300 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PCDH7 Polyclonal antibody
Uniprot No.
Target Names
PCDH7
Alternative Names
BH Pcdh antibody; BH protocadherin antibody; BH-Pcdh antibody; BHPCDH antibody; Brain heart protocadherin antibody; Brain-heart protocadherin antibody; PCDH 7 antibody; PCDH7 antibody; PCDH7_HUMAN antibody; Protocadherin 7 antibody; Protocadherin-7 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protocadherin-7 protein (906-1032AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PCDH7 Antibody (Product code: CSB-PA017536LA01HU) is Non-conjugated. For PCDH7 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA017536LB01HU PCDH7 Antibody, HRP conjugated ELISA
FITC CSB-PA017536LC01HU PCDH7 Antibody, FITC conjugated
Biotin CSB-PA017536LD01HU PCDH7 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:200-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. The findings indicate that low PCDH7 expression is a potential prognostic biomarker for primary non-muscle invasive bladder cancer PMID: 27070091
  2. we report that the PROTOCADHERIN PCDH7 is overexpressed frequently in Non-small cell lung cancer tumors where this event is associated with poor clinical outcome PMID: 27821484
  3. protocadherin 7 may play important roles in the invasion and metastasis of gastric cancer. PMID: 28381163
  4. Two SNPs rs13146789 and rs13109270 of PCDH7 showed strong association with musical aptitude and inner ear development and neurocognitive functions. PMID: 24614497
  5. Pcdh7 plays a key role in osteoclastogenesis by promoting cell-cell fusion PMID: 25446128
  6. PCDH7 is up-regulation in bone metastatic breast cancer tissues. PMID: 23751349
  7. Methylation of polycomb groups target genes is an early event in urothelial carcinogenesis in young patients. PMID: 23369722

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Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Expressed predominantly in brain and heart and at lower levels in various other tissues.
Database Links

HGNC: 8659

OMIM: 602988

KEGG: hsa:5099

STRING: 9606.ENSP00000441802

UniGene: Hs.479439

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