Recombinant Human Protocadherin-7 (PCDH7), partial

Code CSB-YP017536HU
MSDS
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Source Yeast
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Code CSB-EP017536HU
MSDS
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Source E.coli
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Code CSB-EP017536HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP017536HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP017536HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
PCDH7
Uniprot No.
Alternative Names
BH Pcdh; BH protocadherin; BH-Pcdh; BHPCDH; Brain heart protocadherin; Brain-heart protocadherin; PCDH 7; PCDH7; PCDH7_HUMAN; Protocadherin 7; Protocadherin-7
Species
Homo sapiens (Human)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Gene References into Functions
  1. The findings indicate that low PCDH7 expression is a potential prognostic biomarker for primary non-muscle invasive bladder cancer PMID: 27070091
  2. we report that the PROTOCADHERIN PCDH7 is overexpressed frequently in Non-small cell lung cancer tumors where this event is associated with poor clinical outcome PMID: 27821484
  3. protocadherin 7 may play important roles in the invasion and metastasis of gastric cancer. PMID: 28381163
  4. Two SNPs rs13146789 and rs13109270 of PCDH7 showed strong association with musical aptitude and inner ear development and neurocognitive functions. PMID: 24614497
  5. Pcdh7 plays a key role in osteoclastogenesis by promoting cell-cell fusion PMID: 25446128
  6. PCDH7 is up-regulation in bone metastatic breast cancer tissues. PMID: 23751349
  7. Methylation of polycomb groups target genes is an early event in urothelial carcinogenesis in young patients. PMID: 23369722

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Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Expressed predominantly in brain and heart and at lower levels in various other tissues.
Database Links

HGNC: 8659

OMIM: 602988

KEGG: hsa:5099

STRING: 9606.ENSP00000441802

UniGene: Hs.479439

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