PCP4 Antibody, HRP conjugated

1. PCP4 promoter was one of the most hypomethylated in aldosterone-producing adenoma and PCP4 transcription may be associated with demethylation as well as with CEBPA in APAs. PMID: 29294065
2. PCP4/PEP19 has a role in promoting migration, invasion and adhesion in human breast cancer cells PMID: 27384474
3. Data indicated that PCP4/PEP19 regulates apoptosis but exact mechanism is still unknown. PMID: 25153723
4. PCP4 protein is highly expressed in the olfactory bulb and caudate putamen and PCP4 expressing cells in the brain are of neuronal origin. PMID: 24954028
5. PCP4 is a regulator of aldosterone production in normal, hyperplastic, and neoplastic human adrenocortical cells. PMID: 24403568
6. This study demonstrate that Pcp4 overexpression extended these effects later in development by modulating genes in line with the maturation of neurons in the cerebellum. PMID: 24291518
7. The calmodulin regulator protein, PEP-19, sensitizes ATP-induced Ca2+ release. PMID: 23204517
8. Data show that Pcp4 overexpression induces precocious neuronal differentiation, and is associated with an increase in CaMKIIdelta activation. PMID: 21491429
9. The PCP4 promoter is activated by Trichostatin A (TSA) treatment according to promoter reporter assays in HEK 293 cells. PMID: 20494980
10. PEP-19 has the potential to alter the Ca2+-binding dynamics of free CaM and CaM that is bound to other target proteins PMID: 14551202

Show More

Hide All

HGNC: 8742

OMIM: 601629

KEGG: hsa:5121

STRING: 9606.ENSP00000329403

UniGene: Hs.80296