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PCYOX1 Antibody

Datasheet
Code CSB-PA017652GA01HU
Size $600
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Product Details

Uniprot No.
Q9UHG3
Target Names
PCYOX1
Alternative Names
EC 1.8.3.5 antibody; KIAA0908 antibody; PCL1 antibody; PCYOX_HUMAN antibody; PCYOX1 antibody; Prenylcysteine lyase antibody; Prenylcysteine oxidase 1 antibody; Prenylcysteine oxidase precursor antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human PCYOX1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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PCYOX1 Proteins

Customer Reviews and Q&A

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Target Background

Function
Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine.
Gene References into Functions
  1. Elevated prenylcysteine oxidase 1 (PCYOX1) activity could help to propagate the oxidative burden of low density lipoproteins (LDLs), thus making PCYOX1 a potential pharmacological target and a new biomarker in cardiovascular disease [Review]. PMID: 28930587
  2. initial studies of the kinetic mechanism and stereospecificity of this unusual enzyme PMID: 12186880
  3. Addition of the substrate farnesylcysteine to lipoprotein resulted in a time-dependent generation of H(2)O(2) which was stronger in very low density lipoprotein (VLDL) than in LDL or HDL, reflecting the greater protein content of PCL1 in VLDL. PMID: 19253276
Subcellular Location
Lysosome.
Protein Families
Prenylcysteine oxidase family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 20588

OMIM: 610995

KEGG: hsa:51449

STRING: 9606.ENSP00000387654

UniGene: Hs.567502

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