PDCD2L Antibody

Code CSB-PA871560ESR2HU
Size US$166
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Image
  • Western blot
    All lanes: PDCD2L antibody at 1.69µg/ml
    Lane 1: Hela whole cell lysate
    Lane 2: MCF-7 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 39 kDa
    Observed band size: 39 kDa

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA871560ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA871560ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PDCD2L Polyclonal antibody
Uniprot No.
Target Names
PDCD2L
Alternative Names
PDCD2L antibody; Programmed cell death protein 2-like antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Programmed cell death protein 2-like protein (1-358AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Over-expression suppresses AP1, CREB, NFAT, and NF-kB transcriptional activation, and delays cell cycle progression at S phase.
Gene References into Functions
  1. Findings uncover the existence of an extra-ribosomal complex consisting of PDCD2L, RPS2, and PRMT3 and support a role for PDCD2L in the late maturation of 40S ribosomal subunits. PMID: 27697862
  2. To study the role of PDCD2_C domain in apoptosis, the cDNAs of two isoforms of PDCD2 and MGC13096 were cloned. PDCD2 (NM_002598) was over expressed when endothelial cells treated with leukotriene D4 or natural killer cells were activated by IL-2. PMID: 16311922
  3. MGC13096 over-expression restrained proliferation of HEK293T cells. DNA/flow cytometry analysis showed that the over-expression of MGC13096 severely delays cell cycle progression at S phase. PMID: 17393540
  4. Overexpression of PDCD2-like gene attenutates TNF-alpha release in Daudi cells PMID: 18486760
Tissue Specificity
Higher expression in lung, colon, mammary gland, cervix, stomach and small intestine.
Database Links

HGNC: 28194

OMIM: 615661

KEGG: hsa:84306

STRING: 9606.ENSP00000246535

UniGene: Hs.515344

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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