PDLIM7 Antibody

1. In enigma siRNA-transfected cells, cell viability, and the protein levels of AKT and survivin decreased. PMID: 29848705
2. LMOD1, SYNPO2, PDLIM7, PLN, and SYNM down-regulation reflect the altered phenotype of smooth muscle cells in vascular disease and could be early sensitive markers of SMC dedifferentiation. PMID: 27470516
3. Molecular basis of the overactive osteogenic process may at least in part involve a deregulation of the LMP-related pathway in calvarial cells. PMID: 22982077
4. The results showed that LMP-1 inhibited cell apoptosis and induced survivin expression in nasal natural killer/T-cell lymphoma PMID: 25760809
5. The results suggest local transduction with LMP-1 gene promotes osteogenesis and mineralization in distraction osteogenesis. PMID: 25641592
6. LMP-1 mRNA level was regulated in a dose-dependent manner after transfection PMID: 25336289
7. These results are consistent with a model in which binding of OspE to PDLIM7 during infection regulates the activity of PKC isoforms that bind to the PDLIM7 LIM domain. PMID: 25124035
8. LMP1 expression suppressed the expression of Runx2 and BMP-2 in OS cells. PMID: 24762763
9. High Enigma expression is associated with breast neoplasms. PMID: 24466333
10. A direct interaction of Jab1 with LMP-1, is reported. PMID: 24078030
11. Gene transfer of LMP3 upregulated Alkaline Phosphatase, Bone Sialoprotein and BMP2 gene expression and increased in vitro matrix mineralization in human PDL cell line. PMID: 22241179
12. LMP3 induced the successful osteogenic differentiation of AFSC by inducing the expression of osteogenic markers and osteospecific transcription factors. PMID: 23097599
13. findings indicate the existence of a new cell cycle-associated signaling pathway in which LMP1 regulates ERK-mediated Op18/stathmin signaling PMID: 22417000
14. results suggested that LMP3 could affect the fine balance between cell proliferation/differentiation of mesenchymal cells mostly by modulating the TGF-beta1 signaling pathway PMID: 21061915
15. SRF and Enigma coexpressed with MDM2 but not p53 in several liver and stomach tumors. PMID: 21060154
16. LMP1 is a downstream gene of TGF-beta1, involved in periodontal ligament cell proliferation. PMID: 20348040
17. isolated the complementary DNA (cDNA) for the human homologue of LMP-1 from an adult human heart cDNA library and showed that when overexpressed it is osteoinductive PMID: 11874232
18. LIM-1 potentiates bone morphogenetic protein responsiveness via a novel interaction with Smurf1 resulting in decreased ubiquitination of Smads PMID: 16611643
19. Enigma is involved in insulin-induced Glut 4 translocation by regulating cortical actin remodeling. PMID: 16803868
20. Authors hypothesize that the HIV-1 TAT interacting protein can fuse with PDLIM7 and that the fusion proteins could be easily transduced through biological membranes and have biological activity. PMID: 17126496
21. When transferred into mouse muscle fibers, a truncated form of LMP-1 induces pluripotent myoblastic C2C12 cells to differentiate into osteoblastic lineage. PMID: 17805464
22. LMP-1 was expressed primarily in predentin, odontoblasts and blood vessel endothelial cells of healthy teeth. LMP-1 expression was found in unmineralized reparative dentin, odontoblast-like cells and pulp fibroblasts in teeth with caries and pulpitis. PMID: 18215669
23. These studies provide evidence that overexpression of IGFBP-6 suppresses human and murine osteoblast differentiation, that IGFBP-6 and LMP-1 physically interact, and supports the conclusion that this interaction may be functionally relevant. PMID: 18395833
24. LMP1 mediates serine 256 phosphorylation and nuclear entry of Annexin A2 via PLC-PKCalpha/PKCbeta pathway. PMID: 18412141
25. Immunofluorescence stained cell numbers are increased after 20 MOI AdLMP1-GFP infection concordant with upregulation of mRNA expression. PMID: 18618069
26. absence of any hexosamines (N-acetyl glucosamine or N-acetyl galactosamine) in chemical composition analysis of LMP-1 protein revealed that there is little or no post-translational glycosylation of the LMP-1 polypeptide in lung carcinoma cells PMID: 18989571
27. PAR-2 is a possible mediator cooperating with LMP-1 and MMP9 to influence the progression of nasopharyngeal carcinoma by inducing angiogenesis and promoting lymph node metastasis. PMID: 19269113

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HGNC: 22958

OMIM: 605903

KEGG: hsa:9260

STRING: 9606.ENSP00000348099

UniGene: Hs.533040