PDSS2 Antibody, HRP conjugated

1. Results indicate PDSS2 gene which regulates coffee consumption by regulating the expression of the genes linked to caffeine metabolism. PMID: 27561104
2. PDSS2 encodes a putative tumor suppressor, and its expression is regulated by hypermethylation of its promoter in gastric cancer cells. PMID: 25330808
3. Decreased PDSS2 expression is an unfavorable prognostic factor for hepatocellular carcinoma, and PDSS2 has potent anticancer activity in HCC tissues and HepG2 cells. PMID: 25780306
4. Decreased PDSS2 mRNA levels were detected in HCC tissues of 56 patients, correlated with shorter disease-specific survival, and was identified as an independent prognostic factor PMID: 25189544
5. PDSS2 has tumor-suppressing activity in human lung cancer cells by enhancing apoptosis and inhibiting tumorigenic capacity. PMID: 24608273
6. Human PDSS2 polymorphisms are associated with podocyte diseases. A deficiency of coenzyme Q10 is manifested in lymphoblastoid cell lines derived from focal segmental glomerulosclerosis patients. PMID: 23926186
7. Loss of PDSS2 expression is associated with non-small cell lung cancer. PMID: 23312889
8. Data show that expression of either dlp1 or dps1 recovered the thermo-sensitive growth of an E. coli ispB(R321A) mutant and restored IspB activity and production of Coenzyme Q-8. PMID: 20051244
9. murine and human solanesyl and decaprenyl diphosphate synthases are heterotetramers composed of newly characterized hDPS1 (mSPS1) and hDLP1 (mDLP1). PMID: 16262699
10. Expression of PDSS2 is downregulated in human gastric cancer. PDSS2 may be a potent gastric cancer growth suppressor in vitro acting through apoptosis pathways. PMID: 19209031

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HGNC: 23041

OMIM: 610564

KEGG: hsa:57107

STRING: 9606.ENSP00000358033

UniGene: Hs.745008