PEX2 Antibody

Code CSB-PA003742
Size US$119
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  • Western Blot analysis of A549 cells using Peroxin 2 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
PEX2
Alternative Names
PEX2; PAF1; PMP3; PMP35; PXMP3; RNF72; Peroxisome biogenesis factor 2; 35 kDa peroxisomal membrane protein; Peroxin-2; Peroxisomal membrane protein 3; Peroxisome assembly factor 1; PAF-1; RING finger protein 72
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the N-terminal region of Human Peroxin 2.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Somewhat implicated in the biogenesis of peroxisomes.
Gene References into Functions
  1. PEX2 is required for peroxisome autophagy during starvation. PMID: 27597759
  2. the carrier frequencies for two PEX2 mutations causative of the severe Zellweger syndrome spectrum phenotype in Ashkenazi Jews PMID: 23590336
  3. Ischemic wound healing is retarded in mice subjected to recombinant PEX2 injections or viral transduction with PEX2-lentivurus. PMID: 21903356
  4. Genetic screening of PEX2 and other PEX genes involved in peroxisomal biogenesis is warranted in children and adults with ARCA PMID: 21392394
  5. The cause of the syndrome in this patient was a point mutation that resulted in the premature termination of peroxisome assembly factor-1. PMID: 1546315

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Involvement in disease
Peroxisome biogenesis disorder complementation group 5 (PBD-CG5); Peroxisome biogenesis disorder 5A (PBD5A); Peroxisome biogenesis disorder 5B (PBD5B)
Subcellular Location
Peroxisome membrane; Multi-pass membrane protein.
Protein Families
Pex2/pex10/pex12 family
Database Links

HGNC: 9717

OMIM: 170993

KEGG: hsa:5828

STRING: 9606.ENSP00000349543

UniGene: Hs.437966

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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