PEX2 Antibody

Code CSB-PA003742
Size US$100
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  • Western Blot analysis of A549 cells using Peroxin 2 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
PEX2
Alternative Names
PEX2; PAF1; PMP3; PMP35; PXMP3; RNF72; Peroxisome biogenesis factor 2; 35 kDa peroxisomal membrane protein; Peroxin-2; Peroxisomal membrane protein 3; Peroxisome assembly factor 1; PAF-1; RING finger protein 72
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the N-terminal region of Human Peroxin 2.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Somewhat implicated in the biogenesis of peroxisomes.
Gene References into Functions
  1. PEX2 is required for peroxisome autophagy during starvation. PMID: 27597759
  2. the carrier frequencies for two PEX2 mutations causative of the severe Zellweger syndrome spectrum phenotype in Ashkenazi Jews PMID: 23590336
  3. Ischemic wound healing is retarded in mice subjected to recombinant PEX2 injections or viral transduction with PEX2-lentivurus. PMID: 21903356
  4. Genetic screening of PEX2 and other PEX genes involved in peroxisomal biogenesis is warranted in children and adults with ARCA PMID: 21392394
  5. The cause of the syndrome in this patient was a point mutation that resulted in the premature termination of peroxisome assembly factor-1. PMID: 1546315

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Involvement in disease
Peroxisome biogenesis disorder complementation group 5 (PBD-CG5); Peroxisome biogenesis disorder 5A (PBD5A); Peroxisome biogenesis disorder 5B (PBD5B)
Subcellular Location
Peroxisome membrane; Multi-pass membrane protein.
Protein Families
Pex2/pex10/pex12 family
Database Links

HGNC: 9717

OMIM: 170993

KEGG: hsa:5828

STRING: 9606.ENSP00000349543

UniGene: Hs.437966

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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