PIGM Antibody

Datasheet

Code	CSB-PA017976GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

Q9H3S5

Target Names

PIGM

Alternative Names

PIGM antibody; GPI mannosyltransferase 1 antibody; EC 2.4.1.- antibody; GPI mannosyltransferase I antibody; GPI-MT-I antibody; Phosphatidylinositol-glycan biosynthesis class M protein antibody; PIG-M antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human PIGM

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.

Gene References into Functions

B cells but not red cells are glycosylphosphatidylinositol deficient in PIGM-associated inherited glycosylphosphatidylinositol deficiency, caused by a core promoter mutation that abrogates Sp1 binding. PMID: 25293775
Studies indicate that mutations in PGM1 by exome sequencing cause hypoglycemia and liver abnormalities. PMID: 23329837
Mutation substantially reduces transcription of PIGM and blocks mannosylation of glycosylphosphatidylinositol(GPI), leading to partial but severe deficiency of GPI. PMID: 16767100

Involvement in disease

Glycosylphosphatidylinositol deficiency (GPID)

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Protein Families

PIGM family

Database Links

HGNC: 18858

OMIM: 610273

KEGG: hsa:93183

STRING: 9606.ENSP00000357069

UniGene: Hs.552810

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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