PLEK2 Antibody

Code CSB-PA018153GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
PLEK2
Alternative Names
Pleckstrin 2 (mouse) homolog antibody; Pleckstrin 2 antibody; Pleckstrin-2 antibody; PLEK 2 antibody; PLEK2 antibody; PLEK2_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human PLEK2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May help orchestrate cytoskeletal arrangement. Contribute to lamellipodia formation.
Gene References into Functions
  1. expression of PLEK2, the strongest gene to classify melanoma patients, in CD45(-) subsets illustrates the importance of analyzing whole blood cells for biomarker studies PMID: 21698244
  2. Pleckstrin 2 was cloned; its mRNA is widely expressed in a variety of cell lines. PMID: 15865208
  3. pleckstrin-2 uses its modular domains to bind to membrane-associated phosphatidylinositols generated by PI3K, whereby it coordinates with the actin cytoskeleton in lymphocyte spreading and immune synapse formation. PMID: 17008542
  4. These results suggest that PLEK2 is involved in actin rearrangement in a PI 3-kinase dependent manner. PMID: 17658464
Subcellular Location
Cell projection, lamellipodium membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Database Links

HGNC: 19238

OMIM: 608007

KEGG: hsa:26499

STRING: 9606.ENSP00000216446

UniGene: Hs.170473

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