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| Code | CSB-PA809011LD01HU |
| Size | US$299 |
| Uniprot No. | Q8IY17 |
| Protocols | ELISA Protocol |
| Immunogen | Recombinant Human Neuropathy target esterase protein (345-493AA) |
| Raised in | Rabbit |
| Species Reactivity | Human |
| Tested Applications | ELISA |
| Relevance | Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy. |
| Form | Liquid |
| Conjugate | Biotin |
| Storage Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method | >95%, Protein G purified |
| Isotype | IgG |
| Clonality | Polyclonal |
| Alias | Neuropathy target esterase (EC 3.1.1.5) (Patatin-like phospholipase domain-containing protein 6), PNPLA6, NTE |
| Immunogen Species | Homo sapiens (Human) |
| Research Area | Neuroscience |
| Target Names | PNPLA6 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
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| Function | Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy. |
| Involvement in disease | Spastic paraplegia 39, autosomal recessive (SPG39); Boucher-Neuhauser syndrome (BNHS); Laurence-Moon syndrome (LNMS); Oliver-McFarlane syndrome (OMCS) |
| Subcellular Location | Endoplasmic reticulum membrane, Single-pass type I membrane protein, Cytoplasmic side |
| Protein Families | NTE family |
| Tissue Specificity | Expressed in brain, placenta, kidney, neuron and skeletal muscle. Expressed in the developing eye, pituitary and brain. |
| Database Links |
HGNC: 16268 OMIM: 215470 KEGG: hsa:10908 STRING: 9606.ENSP00000407509 UniGene: Hs.631863 |
PNPLA6 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA018285GA01HU | PNPLA6 Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA927839 | PNPLA6 Antibody | Human | ELISA,WB |
| CSB-PA005585 | PNPLA6 Antibody | Human,Mouse,Rat | WB,ELISA |
| CSB-PA006744 | PNPLA6 Antibody | Human,Mouse | WB,ELISA |
| CSB-PA809011LB01HU | PNPLA6 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA809011LC01HU | PNPLA6 Antibody, FITC conjugated | Human | ELISA |
PNPLA6 Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA809011LA01HU | PNPLA6 Antibody | Human | ELISA, IHC, IF |
PNPLA6 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP809011HU CSB-EP809011HU CSB-BP809011HU CSB-MP809011HU |
Recombinant Human Neuropathy target esterase(PNPLA6) ,partial | Yeast E.coli Baculovirus Mammalian cell |
2-hydroxyisobutyryl-HIST1H2BC (K24) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human
2-hydroxyisobutyryl-HIST1H2BC (K34) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human
